LL-37 is a cathelicidin-derived antimicrobial peptide commonly explored in provider-directed programs focused on immune and mucosal wellness. It should be evaluated based on the individual patient, treatment objective, and applicable prescribing information.
What It Is Used For
LL-37 is commonly considered in provider-directed programs focused on the following areas of interest:
Immune Support — Often considered in provider-directed programs designed to support immune wellness objectives.
Antimicrobial Wellness — May be explored within programs focused on antimicrobial and host-defense wellness goals.
Mucosal Support — May be considered for patients whose goals include mucosal and barrier wellness objectives.
LL-37 should be evaluated against applicable prescribing information. Information provided by ALML is intended for healthcare professionals and does not replace independent clinical judgment.
How It Works
LL-37 is a cathelicidin-derived antimicrobial peptide that occurs naturally in humans and has been studied for its association with immune and host-defense processes. Areas of biological activity include:
Areas being studied include:
Antimicrobial and Host-Defense Activity — LL-37 has been studied for its role in host-defense processes, including antimicrobial activity.
Immune and Inflammatory Signaling — Preclinical research has investigated potential effects on immune and inflammatory signaling pathways.
Mucosal and Barrier Function — Research has explored potential effects on mucosal and epithelial barrier processes.
Recovery and Regenerative Pathways — Preclinical research has explored potential effects on cellular processes associated with tissue response and repair.
Clinical use of LL-37 varies by patient-specific factors and applicable prescribing information. The treating healthcare professional remains responsible for all clinical decision-making. This information is educational and does not establish clinical efficacy for any specific use.
Clinical Information
Healthcare professionals should independently evaluate the available evidence, patient-specific factors, potential risks, and applicable regulatory requirements before considering LL-37 for a patient.
Include these considerations:
Patient-Specific Assessment Required — Providers should consider the patient's medical history, current medications, allergies, pregnancy or breastfeeding status, and other relevant clinical factors before use.
Use Within Approved and Appropriate Context — LL-37 should be evaluated against applicable prescribing information and used only where clinically appropriate for the individual patient.
Monitor Tolerance and Relevant Clinical Factors — Providers should monitor patient tolerance and relevant clinical factors throughout the course of use.
Treatment Decisions Remain With the Licensed Healthcare Professional — All treatment, prescribing, and dosing decisions remain solely the responsibility of the appropriately licensed healthcare professional.
ALML provides product and educational information for healthcare professionals. This information is not a substitute for prescribing information, pharmacy labeling, applicable law, or independent clinical judgment.
Available Options
Option 1
Verified formulations and strengths will be updated based on current pharmacy availability.
Dosing & Reconstitution
For provider use only. Calculates reconstitution math — does not select or recommend a patient dose.
Product Dosing Schedule
Provider Inputs
Calculated Outputs
Concentration
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Medication amount ÷ diluent mL
Volume to Draw
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Desired dose ÷ concentration
U-100 Syringe Units
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Volume to draw × 100 — 100 syringe units = 1.00 mL · 1 syringe unit = 0.01 mL
| Reference Dose | 0.20 mg once daily |
| Frequency | Daily |
| Dose Unit | mg/day |
| Administrations Per Week | 7 |
Dosing information is provided for healthcare-professional reference only when verified. Patient-specific dosing and prescribing decisions remain the responsibility of the treating healthcare professional.
This tool performs reconstitution/administration math only. It does not select, recommend, or validate a patient dose. Dosing decisions are the responsibility of the prescribing healthcare provider.
Ask ALML
Ask ALML may identify LL-37 as a product for a healthcare professional to explore when the described patient goals involve immune support, antimicrobial wellness, or mucosal support.
The match is informational. Ask ALML is designed to help healthcare professionals navigate the ALML portfolio and identify potentially relevant options for further clinical consideration. It does not diagnose a patient, prescribe treatment, determine medical necessity, or select patient-specific dosing.
Submit an order request or ask about availability. A request is not a guaranteed order — every inquiry goes to ALML staff for manual review and follow-up.
ALML does not guarantee that any specific therapy can be supplied. Availability is confirmed through manual review of each request.